In vitro degradation and in vivo resorption of dicalcium phosphate cement based grafts
نویسندگان
چکیده
منابع مشابه
CALCIUM PHOSPHATE CEMENT: STUDY OF (BETA-TRICALCIUM PHOSPHATE, DICALCIUM PHOSPHATE AND CALCIUM CARBONATE SYSTEM
Calcium phosphate cements (CPCs), using B-tricalcium phosphate (ß-TCP, Ca3 (P04)2), dicalcium phosphate (DCP, CaHP04), calcium carbonate (Ca CO3), and hydroxylapatite (HAp, Ca10(P04)6(OH)2) as powder cement and disodium hydrogen phosphate (Na2HP04) solution as liquid component were prepared. After mixing the powder and liquid constituents, injectable and self-setting calcium phosphate cements (...
متن کاملMechanisms of in Vivo Degradation and Resorption of Calcium Phosphate Based Biomaterials
Calcium phosphate ceramic materials are extensively used for bone replacement and regeneration in orthopedic, dental, and maxillofacial surgical applications. In order for these biomaterials to work effectively it is imperative that they undergo the process of degradation and resorption in vivo. This allows for the space to be created for the new bone tissue to form and infiltrate within the im...
متن کاملIn vitro ion adsorption and cytocompatibility of dicalcium phosphate ceramics
BACKGROUND In vitro cell testing of degradable bioceramics such as brushite or monetite is often challenging due to the ion release into or adsorption from the culture medium. These ionic changes are then mostly responsible for cell proliferation and activity, which prohibits the investigation of effects originating from surface topography or further material modifications. METHODS Here, we a...
متن کاملHigh early strength calcium phosphate bone cement: effects of dicalcium phosphate dihydrate and absorbable fibers.
Calcium phosphate cement (CPC) sets in situ to form resorbable hydroxyapatite with chemical and crystallographic similarity to the apatite in human bones, hence it is highly promising for clinical applications. The objective of the present study was to develop a CPC that is fast setting and has high strength in the early stages of implantation. Two approaches were combined to impart high early ...
متن کاملEffect of ultrafine poly(ε-caprolactone) fibers on calcium phosphate cement: in vitro degradation and in vivo regeneration
We incorporated ultrafine polymer fibers into calcium phosphate cement (CPC) to improve the resorption rate of CPC with fiber degradation. Different weight percentages of electrospun poly(ε-caprolactone) fibers (0%, 3%, and 7%, named as ultrafine fiber-incorporated CPC0 [UFICPC0], UFICPC3, and UFICPC7) were included into preset CPC specimens for in vitro immersion in lipase phosphate-buffered s...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2015
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2015.08.031